Biotin anti-human CD349 (Frizzled-9)

CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originally described as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/beta-catenin pathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletal muscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteins play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. FZD9 isan important factor fornervous system development and is critical for hippocampal development.

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SPECIFICATIONS

Catalog Number

326704

Size

100 microg

Applications

FC

Hosts

Mouse

Reactivities

Hum

Conjugates

Biotin

Clone

W3C4E11

Antigen

WERI-RB-1 retinoblastoma cells

Gene Id

8322

Isotype

Mouse IgM, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?2.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C. Do not freeze.

Alternative Names

Frizzled-9 receptor, Frizzled-9, Fz9, FZD9, FzE6, hFz9

Regulatory Status

RUO