Biotin anti-human CD286 (TLR6)

Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizing pathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immune systems. To date a total of 12 TLRs have been identified. Toll-like receptor 6 (TLR6), known as CD286, is one of the important receptors. TLR6 is colocalized with TLR2 on the cell surface of monocytes/macrophages, dendritic cells, granulocytes. The TLR2/TLR6 complex plays a role in the innate immune response to diacylated lipoprotein and peptidoglycan antigens.

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SPECIFICATIONS

Catalog Number

334705

Size

25 microg

Applications

FC

Hosts

Mouse

Reactivities

Hum

Conjugates

Biotin

Clone

TLR6.127

Antigen

Human TLR6 transfected Ba/F3 cells

Gene Id

10333

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 2.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C. Do not freeze.

Alternative Names

TLR6

Regulatory Status

RUO