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Biotin anti-human CD262 (DR5, TRAIL-R2)

Biotin anti-human CD262 (DR5, TRAIL-R2)

Cat no: 307404

Supplier: BioLegend
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DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-alpha, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
Catalogue number: 307404
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Conjugates: Biotin
Size: 100 microg
Clone: DJR2-4 (7-8)
Gene: 8795
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 2.0 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. Do not freeze.
Concentration: 0.5 mg/ml
Antigen: Extracellular domain of DR5-human IgG1 Fc fusion protein
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: DR5, TRAIL-R2, TRICK2, KILLER, TNFRS10B
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