Biotin anti-human CD218a (IL-18Ralpha)

IL-18 receptor is composed of an alpha and a beta subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor alpha chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis.

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SPECIFICATIONS

Catalog Number

313806

Size

100 microg

Applications

FC, IHC

Hosts

Mouse

Reactivities

Hum

Conjugates

Biotin

Clone

H44

Antigen

Human NK cell line NK0 constitutively expressing IL-18 receptors

Gene Id

8809

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Alternative Names

IL-18Ra, IL-18 receptor 1, CDw218a

Regulatory Status

RUO