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Beta-Amyloid [1-16] Antibody

Beta-Amyloid [1-16] Antibody

Cat no: 250921

Supplier: ABBIOTEC
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Beta-amyloid production results from cleavage in the e, Xenopus/Amphibian,tracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. The (1-16) fragment is the amino terminus of beta-amyloid. The binding of this antibody to amyloid beta-peptide depends on the presence of residues 10-16.
Catalogue number: 250921
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P05067
Antigen: KLH-conjugated synthetic peptide encompassing the sequence (1-16) of human Beta Amyloid.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Mouse Polyclonal Antibody
Isotype: Mouse Ig
Additional info: APP; ABPP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; Protease ne, Xenopus/Amphibian,in-II; PN-II; APPI; PreA4
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