Reactivities: | Human |
Presku: | AAP50108 |
Size: | 100ug |
Weight: | 51kDa |
Gene: | 144453 |
Format: | Lyophilized powder |
Target: | BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. |
Alternative names: | MGC13168; MGC40411; VMD2L3 |