Reactivities: | Human |
Presku: | AAP39569 |
Size: | 100ug |
Weight: | 91kDa |
Gene: | 53335 |
Format: | Lyophilized powder |
Target: | BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. |
Alternative names: | BCL11A-L; BCL11A-S; BCL11A-XL; CTIP1; EVI9; FLJ10173; FLJ34997; HBFQTL5; KIAA1809; ZNF856 |