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BANF1 Antibody (OAPB00480)

BANF1 Antibody (OAPB00480)

Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA. Despite its predicted molecular weight, BANF1 often migrates at a higher size in SDS-PAGE.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, IF, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Presku

OAPB00480

Target

(CT) Barrier to autointegration factor

Alternative Names

BANF1 (CT); Barrier to autointegration factor 1; BAF; breakpoint cluster region protein 1

SUPPLIER INFO

Aviva Systems Biology Incorporated

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