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BACE2 (beta-site APP-cleaving enzyme 2) Blocking Peptide (the N terminal of BACE2)(100ug)

BACE2 (beta-site APP-cleaving enzyme 2) Blocking Peptide (the N terminal of BACE2)(100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-BACE2 Antibody(ARP46853_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP46853
Size: 100ug
Weight: 37kDa
Gene: 25825
Format: Lyophilized powder
Target: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
Alternative names: AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP