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B7-H4 Antibody

B7-H4 Antibody

Cat no: 250473

Supplier: ABBIOTEC
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Immune costimulatory protein B7-H4 (B7-H4) is e, Xenopus/Amphibian,pressed on the surface of a variety of immune cells and functions as a negative regulator of T cell response. By arresting cell cycle, B7-H4 inhibits growth, cytokine secretion and cytoto, Xenopus/Amphibian,icity development. When e, Xenopus/Amphibian,pressed on the cell surface of tumor macrophages, B7-H4 plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. B7-H4 is also involved in promoting epithelial cell transformation. B7-H4 can be a predictive marker for renal cell carcinoma.
Catalogue number: 250473
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q7Z7D3
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human B7-H4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: V-set domain-containing T-cell activation inhibitor 1; Immune costimulatory protein B7-H4; B7h.5; T-cell costimulatory molecule B7, Xenopus/Amphibian,; Protein B7S1; VTCN1; B7H4
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