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ATXN7L3 (ataxin 7-like 3 ) Blocking Peptide (the middle region of ATXN7L3)(100ug)

ATXN7L3 (ataxin 7-like 3 ) Blocking Peptide (the middle region of ATXN7L3)(100ug)

This is a synthetic peptide designed for use in combination with anti-ATXN7L3 Antibody (ARP67018_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP67018

Target

ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.

Weight

38kDa

Gene Id

56970

Alternative Names

DKFZp761G2113

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