Reactivities: | Human, Rat |
Presku: | AAP59072 |
Size: | 100ug |
Weight: | 76kDa |
Gene: | 312647 |
Format: | Lyophilized powder |
Target: | Atg7 functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. It forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. It also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3. |
Alternative names: | Apg7l |