Presku: | AAP57977 |
Size: | 100 ug |
Weight: | 31kDa |
Gene: | 22809 |
Format: | Lyophilized powder |
Target: | ATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma. |
Alternative names: | ATFX; FLJ34666; HMFN0395 |