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ATF3 Human - Recombinant Human Activating Transcription Factor-3 (5ug)

ATF3 Human - Recombinant Human Activating Transcription Factor-3 (5ug)

Product Introduction: ATF3 belongs to the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. ATF3 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in numerous viral and cellular promoters. Multiple transcript variants encoding two different isoforms are known for this gene. The longer isoform represses transcription from promoters with ATF binding elements instead of activating it. The shorter isoform (deltaZip2) which stimulates transcription by sequestering inhibitory co-factors away from the promoter has no leucine zipper protein-dimerization motif and does not bind to DNA.
Product Description: ATF3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 181 amino acids (1-181) and having a molecular mass of 20.6 kDa. The ATF3 is purified by proprietary chromatographic techniques.

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SPECIFICATIONS

Size

5ug

Format

ATF3 is supplied as a sterile filtered clear solution.

Presku

OOPA00182

Alternative Names

Activating transcription factor 3; cyclic AMP-dependent transcription factor ATF-3; FLJ41705.

SUPPLIER INFO

Aviva Systems Biology Incorporated

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