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ATF-1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251171

ATF-1 Antibody

Activating transcription factor 1 (ATF-1) is a protein that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF-1 binds to the Ta, Xenopus/Amphibian,-responsive element (TRE) of HTLV-I. ATF-1 mediates PKA-induced stimulation of CRE-reporter genes. Defects in ATF-1 are linked to angiomatoid fibrous histiocytoma (AFH). AFH is a distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth.

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SPECIFICATIONS

Catalog Number

251171

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Ch/Bird, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ATF-1.

Isotype

Rabbit Ig

Accession

P18846

Additional Info

ATF-1; Activating Transcription Factor-1; ATF1; Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36

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