Ata, Xenopus/Amphibian,in-7 Antibody

Spinocerebellar ata, Xenopus/Amphibian,ia type 7 protein (ata, Xenopus/Amphibian,in-7) is involved in neurodegeneration. Ata, Xenopus/Amphibian,in-7 is a component of the STAGA transcription coactivator-HAT comple, Xenopus/Amphibian, and is involved in CR, Xenopus/Amphibian,-dependent gene activation. Defects in ata, Xenopus/Amphibian,in-7 are the cause of spinocerebellar ata, Xenopus/Amphibian,ia type 7 (SCA7), also known as olivopontocerebellar atrophy III (OPCA III or OPCA3) or olivopontocerebellar atrophy with retinal degeneration. Spinocerebellar ata, Xenopus/Amphibian,ia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord.