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ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1) Blocking Peptide (the middle region of ASZ1)(100ug)

ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1) Blocking Peptide (the middle region of ASZ1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-ASZ1 Antibody(ARP52537_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP52537
Size: 100ug
Weight: 53kDa
Gene: 136991
Format: Lyophilized powder
Target: ASZ1 plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity.ASZ1 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.ASZ1 is required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons.ASZ1 may act by mediating protein-protein interactions during germ cell maturation.
Alternative names: ALP1; ANKL1; C7orf7; GASZ; MGC26634; Orf3
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