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ASPP2 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251646

ASPP2 Antibody

Apoptosis-stimulating of p53 protein 2 (ASPP2) is a regulator that plays a central role in regulation of apoptosis and cell growth. ASPP2 regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. ASPP2 inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. ASPP2 impedes cell cycle progression at G2/M. The apoptosis-stimulating activity of ASPP2 is inhibited by its interaction with DD, Xenopus/Amphibian,42.

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SPECIFICATIONS

Catalog Number

251646

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ASPP2.

Isotype

Rabbit Ig

Accession

Q13625

Additional Info

ASPP2; Apoptosis-stimulating of p53 protein 2; Tumor suppressor p53-binding protein 2; p53-binding protein 2; p53BP2; 53BP2; Bcl2-binding protein; Bbp; Renal carcinoma antigen NY-REN-51; TP53BP2; BBP

SUPPLIER INFO

ABBIOTEC

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