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ASCL1 (achaete-scute complex homolog 1 (Drosophila)) Blocking Peptide (100ug)

ASCL1 (achaete-scute complex homolog 1 (Drosophila)) Blocking Peptide (100ug)

This is a synthetic peptide designed for use in combination with anti-ASCL1 antibody (Catalogue #: ARP32355_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100 ug

Format

Lyophilized powder

Presku

AAP32355

Target

ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.

Weight

25kDa

Gene Id

429

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