Home  >  Products  >  Arhgef4 (Rho guanine nucleotide exchange factor (GEF) 4 ) Blocking Peptide (the N terminal of Arhgef4)(100ug)
Arhgef4 (Rho guanine nucleotide exchange factor (GEF) 4 ) Blocking Peptide (the N terminal of Arhgef4)(100ug)

Arhgef4 (Rho guanine nucleotide exchange factor (GEF) 4 ) Blocking Peptide (the N terminal of Arhgef4)(100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-Arhgef4 Antibody (ARP59254_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP59254
Size: 100ug
Weight: 57kDa
Gene: 226970
Format: Lyophilized powder
Target: Arhgef4 acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion By similarity. It is required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Arhgef4 is involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Alternative names: 9330140K16Rik; Asef; ENSMUSG00000070955
See Full Product Listings >