Reactivities: | Human |
Presku: | AAP54566 |
Size: | 100ug |
Weight: | 36kDa |
Gene: | 384 |
Format: | Lyophilized powder |
Target: | Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. ARG2 (type II isoform) is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. |