Reactivities: | Human |
Presku: | AAP64428 |
Size: | 100ug |
Weight: | 171kDa |
Gene: | 9716 |
Format: | Lyophilized powder |
Target: | AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. |
Alternative names: | DKFZp686B23123; IBP160; KIAA0560; fSAP164 |