Reactivities: | Human |
Presku: | AAP53808 |
Size: | 100ug |
Weight: | 23kDa |
Gene: | 83464 |
Format: | Lyophilized powder |
Target: | This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. |
Alternative names: | APH-1B; DKFZp564D0372; FLJ33115; PRO1328; PSFL; TAAV688 |