Supplier:
Aviva Systems Biology IncorporatedAPEX1 (APEX nuclease (multifunctional DNA repair enzyme) 1) Blocking Peptide (100ug)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100 ug
Format
Lyophilized powder
Presku
AAP32651
Target
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells.
Weight
35kDa
Gene Id
328
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