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APEH (N-acylaminoacyl-peptide hydrolase) Blocking Peptide (the middle region of APEH)(100ug)

APEH (N-acylaminoacyl-peptide hydrolase) Blocking Peptide (the middle region of APEH)(100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-APEH Antibody(ARP48182_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP48182
Size: 100ug
Weight: 81kDa
Gene: 327
Format: Lyophilized powder
Target: APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Alternative names: ACPH; APH; D3F15S2; D3S48E; DNF15S2; MGC2178; OPH