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APC anti-human CD262 (DR5, TRAIL-R2)

APC anti-human CD262 (DR5, TRAIL-R2)

Cat no: 307407

Supplier: BioLegend
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DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-alpha, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
Catalogue number: 307407
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 25 tests
Clone: DJR2-4 (7-8)
Gene: 8795
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: Extracellular domain of DR5-human IgG1 Fc fusion protein
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: DR5, TRAIL-R2, TRICK2, KILLER, TNFRS10B
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