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APBA1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252076

APBA1 Antibody

Amyloid beta A4 precursor protein-binding family A member 1 (APBA1) functions in synaptic vesicle e, Xenopus/Amphibian,ocytosis by binding to Munc18-1, an essential component of the synaptic vesicle e, Xenopus/Amphibian,ocytotic machinery. APBA1 modulates processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. APBA1 is composed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.

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SPECIFICATIONS

Catalog Number

252076

Size

0.1 mg

Applications

WB

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human APBA1.

Isotype

Rabbit Ig

Accession

Q02410

Additional Info

Amyloid beta A4 precursor protein-binding family A member 1; Neuron-specific , Xenopus/Amphibian,11 protein; Neuronal Munc 18-1-interacting protein 1; Mint-1; Adapter protein , Xenopus/Amphibian,11alpha; APBA1; MINT1; , Xenopus/Amphibian,11

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