Supplier:
Aviva Systems Biology IncorporatedAnti-Voltage Gated Potassium Channel, Kv2.2 Subunit
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SPECIFICATIONS
Size
100 ul
Applications
IHC, WB
Hosts
Rabbit
Reactivities
Rat
Format
Affinity purified, polyclonal antibody
Presku
OAPC00001
Target
Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety of non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993; Yan et al., 2004; Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998; Burger and Ribera, 1996).
Weight
~100kDa
Gene Id
621349
SUPPLIER INFO
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