Supplier:
Aviva Systems Biology IncorporatedAnti-TrkB
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SPECIFICATIONS
Size
100 ul
Applications
WB
Hosts
Rabbit
Reactivities
Rat
Format
Affinity purified polyclonal antibody
Presku
OAPC00072
Target
Tropomyosin-receptor-kinase (TRK) receptors are members of the receptor tyrosine kinase family and include TrkA, TrkB and TrkC. Each of these receptor types has different binding affinities to the neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3). TrkB has the highest affinity to binding BDNF which plays critical roles in the function and survival of neurons in the CNS (Soppet et al., 1991; Klein et al., 1991). Additionally, alterations in expression of TrkB have been associated with Alzheimer's disease (Ferrer et al., 1999; Chen et al., 2008).
Weight
~93kDa
Gene Id
25054
SUPPLIER INFO
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