Supplier:
Aviva Systems Biology IncorporatedAnti-Syntaxin 1A
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SPECIFICATIONS
Size
100 ul
Applications
IHC, WB
Hosts
Mouse
Reactivities
Hum, Rat, Prc
Clone
SP8
Format
Purified mouse monoclonal antibody
Presku
OAPC00068
Target
Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion (Khvotchev et al., 2007). Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010).
Weight
~36kDa
Gene Id
6804
Isotype
IgG<sup>1</sup>
SUPPLIER INFO
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