Supplier:
Aviva Systems Biology IncorporatedAnti-Retinoic Acid Receptor, beta -Isotype
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SPECIFICATIONS
Size
100 ul
Applications
WB
Hosts
Mouse
Reactivities
Hum, Mouse, Rat, Can, Prc
Clone
336
Format
Affinity purified, monoclonal antibody
Presku
OAPC00019
Target
Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXR alpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
Weight
~48kDa
Gene Id
5915
Isotype
IgG<sup>1</sup>
SUPPLIER INFO
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