Supplier:
Aviva Systems Biology IncorporatedAnti-Phospho-Thr<sup>210</sup> Polo-like Kinase 1
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SPECIFICATIONS
Size
100 ul
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat, Bov, Can, ZF/Fish
Format
Affinity purified, polyclonal antibody
Presku
OAPC00221
Target
Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles (van Vugt et al., 2004). Deregulated expression of PLK's is detected in many types of cancer and associated with oncogenesis (Takei et al., 2005). It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210 (van de Weerdt et al., 2005).
Weight
~66kDa
Gene Id
5347
SUPPLIER INFO
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