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Anti-Phospho-Ser<sup>923</sup> GABA<sub>B</sub> R1

Anti-Phospho-Ser<sup>923</sup> GABA<sub>B</sub> R1

Specific for ~102k GABAB R1 phosphorylated at Ser923. Immunolabeling of the GABAB R1 band is completely blocked by lambda -phosphatase treatment. Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephospho-peptide affinity columns.

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SPECIFICATIONS

Size

100 ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov

Format

Affinity purified, polyclonal antibody

Presku

OAPC00165

Target

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.

Weight

~102kDa

Gene Id

81657

SUPPLIER INFO

Aviva Systems Biology Incorporated

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