Supplier:
Aviva Systems Biology IncorporatedAnti-Phospho-Ser<sup>535,539</sup> Interferon- alpha Receptor, Type I, Subunit I
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SPECIFICATIONS
Size
100 ul
Applications
IHC, WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat, Bov, Can, Sheep
Format
Affinity purified, polyclonal antibody
Presku
OAPC00208
Target
Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon- alpha Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
Weight
~110-130kDa
Gene Id
3454
SUPPLIER INFO
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