Supplier:
Aviva Systems Biology IncorporatedAnti-Phospho-Ser<sup>503</sup> Kv3.1, Voltage-Gated, Potassium Channel
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SPECIFICATIONS
Size
100 ul
Applications
IHC, WB
Hosts
Rabbit
Reactivities
Mouse, Rat
Format
Affiinity Purified, Polyclonal antibody
Presku
OAPC00187
Target
Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995; Pongs, 1999; Blaine and Ribera, 1998; Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).
Weight
~100kDa
Gene Id
25327
SUPPLIER INFO
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