Supplier:
Aviva Systems Biology IncorporatedAnti-Phospho-Ser<sup>40</sup> Tyrosine Hydroxylase
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SPECIFICATIONS
Size
100 ul
Applications
IF, IHC, WB
Hosts
Rabbit
Format
Affinity purified, polyclonal antibody
Presku
OAPC00206
Target
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004). The activity of TH is also regulated by phosphorylation (Haycock et al., 1982; Haycock et al., 1992; Jedynak et al., 2002). Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.
Weight
~60kDa
Gene Id
25085
SUPPLIER INFO
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