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Anti-Phospho-Ser<sup>309</sup> Synaptotagmin

Anti-Phospho-Ser<sup>309</sup> Synaptotagmin

Specific for the ~60k-62k synaptotagmin protein phosphorylated at Ser309. Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.

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SPECIFICATIONS

Size

100 ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov, Can, Ch/Bird, ZF/Fish

Format

Affinity purified, polyclonal antibody

Presku

OAPC00198

Target

Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001; Wang et al., 2003). Moreover, recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999; Lee et al., 2004).

Weight

~60kDa-62kDa

Gene Id

25716

SUPPLIER INFO

Aviva Systems Biology Incorporated

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