Supplier:
Aviva Systems Biology IncorporatedAnti-Phospho-Ser<sup>1166</sup> NMDA Receptor NR2B Subunit
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SPECIFICATIONS
Size
100 ul
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat, Can
Format
Affinity purified, polyclonal antibody
Presku
OAPC00180
Target
The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002; Wenthold et al., 2003; Carroll and Zukin, 2002). Overexpression of the NR2B-subunit of the NMDA Receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression (Clayton et al., 2002a; Clayton et al., 2002b). Phosphorylation of Ser1166 is thought to play an essential role in memory and neuronal development.
Weight
~180kDa
Gene Id
24410
SUPPLIER INFO
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