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Anti-Pertussis Toxin antibody, rabbit serum

Cat no: 64-030

Anti-Pertussis Toxin antibody, rabbit serum

Anti-Pertussis Toxin Antibody, Rabbit Serum. Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by Bordetella pertussis. PT catalyzes the ADP-ribosylation of the alpha subunits of the heterotrimeric guanine nucleotide regulatory proteins Gi, Go, and Gt and prevents intracellular signal transduction involving the G proteins. PT consists of one molecule of each S1 (26 kDa), S2 (22 kDa), S3 (22 kDa), S5 (12 kDa) and two molecules of S4 (12 kDa). This antibody is highly purified (>90% pure) from Bordetella pertussis strain Tohama by the method of Skelton & Wong. Cytotoxicity of the PT was confirmed by morphological alteration of CHO cells after treatment with 0.1 ng/ml of PT.

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SPECIFICATIONS

Catalog Number

64-030

Size

100ul

Applications

ELISA, IP, WB

Hosts

Rabbit

Clonality

Polyclonal

Dilutions

WB 1:2000-10000, IP 1:200-500, Dot 1:2000-10000, ELISA 1:10000-20000, Neutralization (assay dependent)

Storage Temp

- 20 degree C

Shipping Temp

4C

SUPPLIER INFO

B-BRIDGE INTERNATIONAL, INC

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