Supplier:
Aviva Systems Biology IncorporatedAnti-Olig1
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SPECIFICATIONS
Size
100 ul
Applications
IHC, IP, WB
Hosts
Rabbit
Reactivities
Mouse, Rat
Format
Affinity purifed polyclonal antibody
Presku
OAPC00047
Target
Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).
Weight
~27kDa
Gene Id
50914
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