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Anti-NMDA Receptor, NR1 Subunit, C2 Splice Variant Insert

Anti-NMDA Receptor, NR1 Subunit, C2 Splice Variant Insert

Specific for the ~36k stargazin protein. Immunolabeling of the stargazin band is blocked by preadsorption with the peptide used as antigen. Prepared from rabbit serum by affinity purification via chromatography on an affinity column to which the C-terminal peptide used as immunogen was coupled.

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SPECIFICATIONS

Size

100 ul

Applications

WB

Hosts

Rabbit

Reactivities

Mouse, Rat

Format

Affinity purified, polyclonal antibody

Presku

OAPC00040

Target

Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002).

Weight

~36kDa

Gene Id

12300

SUPPLIER INFO

Aviva Systems Biology Incorporated

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