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Products Anti-Neurofilament M (NF-M)
| Reactivities: | Human, Mouse, Rat, Chicken/Bird |
| Applications: | Immunofluorescence, Western Blot |
| Presku: | OAPC00029 |
| Size: | 100 ul |
| Weight: | ~145kDa |
| Gene: | 24588 |
| Format: | Total IgY fraction |
| Target: | Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). |
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