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Anti-Neurofilament L (NF-L)

Anti-Neurofilament L (NF-L)

Specific for the ~68k Neurofilament L protein in Western blots and works well on frozen sections, cells in tissue culture and on mildly formalin fixed histological sections. Total IgY fraction.

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SPECIFICATIONS

Size

100 ul

Applications

IF, WB

Reactivities

Hum, Mouse, Rat, Bov, Ch/Bird

Format

Total IgY fraction

Presku

OAPC00027

Target

Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease (2).

Weight

~68kDa

Gene Id

4747

SUPPLIER INFO

Aviva Systems Biology Incorporated

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