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Products Anti-Neurofilament L (NF-L)
| Reactivities: | Human, Mouse, Rat, Bovine, Chicken/Bird |
| Applications: | Immunofluorescence, Western Blot |
| Presku: | OAPC00027 |
| Size: | 100 ul |
| Weight: | ~68kDa |
| Gene: | 4747 |
| Format: | Total IgY fraction |
| Target: | Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease (2). |
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