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Products Anti-Neurofilament H (NF-H)
| Reactivities: | Human, Mouse, Rat, Chicken/Bird |
| Applications: | Immunofluorescence, Western Blot |
| Presku: | OAPC00025 |
| Size: | 100 ul |
| Weight: | ~200kDa |
| Gene: | 4744 |
| Format: | Total IgY fraction |
| Target: | Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (2) and Alzheimer's disease (3). |
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