Supplier:
Aviva Systems Biology IncorporatedAnti-Neurofilament H (NF-H)
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SPECIFICATIONS
Size
100 ul
Applications
IF, WB
Reactivities
Hum, Mouse, Rat, Ch/Bird
Format
Total IgY fraction
Presku
OAPC00025
Target
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (2) and Alzheimer's disease (3).
Weight
~200kDa
Gene Id
4744
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