Interleukin 6 (IL-6) is an important pro-inflammatory and Anti-cytokine expressed by T cells, macrophages and muscle cells. IL-6 signals through a receptor complex containing two receptors, IL-6R alpha and gp130. IL-6 has an important function in promoting fever and can serve to stimulate an immune response to trauma. IL-6 is often used for growth of hybridoma cell lines. IL-6 is active on and cells.
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