Anti-human CD3 FITC/(CD16+CD56) PE Cocktail

CD3: UCHT1 antibody reacts with a combinatorial epitope of CD3epsilon, a 20 kD chain of the CD3/T-cell receptor (TCR) complex found on all mature T lymphocytes, NK-T cells and some thymocytes.CD16: 3G8 antibody reacts with CD16, a 50-65 kD transmembrane or a 48 kD GPI-anchored glycoprotein that is a member of the immunoglobulin superfamily. CD16 is expressed on NK cells, activated monocytes, macrophages, mast cells and neutrophils.CD56: MEM-188 antibody reacts with the 175 - 185 kD isoform of CD56, N-CAM (Neural Cell Adhesion Molecule), which is expressed on NK cells and a subset of CD3+ T cells. CD56 is also expressed in brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56.

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SPECIFICATIONS

Catalog Number

319101

Size

50 tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Clone

UCHT1/3G8/MEM-188

Gene Id

920

Isotype

Mouse IgG1/IgG1/IgG2a

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 microl per million cells or 20 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

This product is guaranteed for nine months. The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Regulatory Status

RUO