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anti-HCV NS4a protein antibody, mouse monoclonal (S4-13)

Cat no: 65-057

anti-HCV NS4a protein antibody, mouse monoclonal (S4-13)

Hepatitis C virus (HCV) is a small (55-65 nm in size), enveloped, positive sense single-stranded RNA virus in the family Flaviviridae and the principal cause of parenteral non-A, non-B hepatitis. The virus genome consists of a single open reading frame of approximately 9,400 bases which encodes a single polyprotein of about 3,010 amino acids (1, 2, 3) . The polyprotein is processed by host cell and viral proteases into four structural proteins (core, envelope1 and 2, and p7) and six non-structural proteins (NS2, 3, 4a, 4b, 5a, and 5b) necessary for viral replication. NS3 serine proteinase is responsible for proteolytic processing of other non-structural proteins. NS4a protein (54 amino acids) forms a comlex with NS3 and functions as a cofactor for NS3 protease activity.\n\nA region of NS4 protein (the nucleotide sequence is shown in ref.4) of HCV genotype 1b expressed in E.coli. The epitope of this antibody was mapped to the N-terminal region of the NS4 protein (NS4a).\n\nIsotype: Mouse IgG2b kappa\n\nApplications \n1. Western blotting \n2. Immunofluorescence staining \n3. ELISA \n\n\n

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SPECIFICATIONS

Catalog Number

65-057

Size

100 ul

Applications

ELISA, IF, WB

Hosts

Mouse

Reactivities

Hum

Clone

S4-13

Gene Id

P26666

Clonality

Monoclonal

Storage Temp

- 20 degree C

Shipping Temp

4C

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