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Anti-Fto(Fat mass and obesity-associated protein)

Anti-Fto(Fat mass and obesity-associated protein)

Specific for the ~58 kDa Fto protein in Western blots of rat testes lysate. The antibody has also been used for immunocytochemistry with neuronal progenitor cells. Protein G purified culture supernatant.

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SPECIFICATIONS

Size

100 ul

Applications

IF, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Clone

5-2H10

Format

Affinity purified monoclonal antibody

Presku

OAPC00112

Target

The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that Fto is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009)

Weight

~58kDa

Gene Id

79068

Isotype

IgG

SUPPLIER INFO

Aviva Systems Biology Incorporated

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