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Anti-Fto(Fat mass and obesity-associated protein)

Anti-Fto(Fat mass and obesity-associated protein)

Supplier: Aviva Systems Biology Incorporated
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Specific for the ~58 kDa Fto protein in Western blots of rat testes lysate. The antibody has also been used for immunocytochemistry with neuronal progenitor cells. Protein G purified culture supernatant.
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunofluorescence, Western Blot
Presku: OAPC00112
Size: 100 ul
Weight: ~58kDa
Clone: 5-2H10
Gene: 79068
Format: Affinity purified monoclonal antibody
Target: The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that Fto is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009)
Isotype: IgG
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