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Anti-Doublecortin (DCX)

Anti-Doublecortin (DCX)

Specific for the ~35 & 45 k doublecortin protein. Affinity purified from tissue culture supernatant.

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SPECIFICATIONS

Size

100 ul

Applications

IF, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov

Clone

30

Format

Affinity purified mouse monoclonal antibody

Presku

OAPC00106

Target

Doublecortin, or DCX, is a microtubule associated protein that is expressed almost exclusively in very early neuronal development (Brown et al., 2003), making it an excellent marker for developing neuronal cells. Defects in the DCX gene lead toX-linked lissencephaly which is characterized by a lack of normal folds on the surface of the brain resulting in a smooth cerebral cortex caused by abnormal migration of neurons during development (des Portes et al., 1998; Gleeson et al., 1998).

Weight

~35 & 45

Gene Id

1641

Isotype

IgG<sup>2a</sup>

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