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Anti-Doublecortin (DCX)

Anti-Doublecortin (DCX)


Supplier: Aviva Systems Biology Incorporated
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Specific for the ~35 & 45 k doublecortin protein. Affinity purified from tissue culture supernatant.
Reactivities: Human, Mouse, Rat, Bovine
Hosts: Mouse
Applications: Immunofluorescence, Western Blot
Presku: OAPC00106
Size: 100 ul
Weight: ~35 & 45
Clone: 30
Gene: 1641
Format: Affinity purified mouse monoclonal antibody
Target: Doublecortin, or DCX, is a microtubule associated protein that is expressed almost exclusively in very early neuronal development (Brown et al., 2003), making it an excellent marker for developing neuronal cells. Defects in the DCX gene lead toX-linked lissencephaly which is characterized by a lack of normal folds on the surface of the brain resulting in a smooth cerebral cortex caused by abnormal migration of neurons during development (des Portes et al., 1998; Gleeson et al., 1998).
Isotype: IgG2a