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Anti-DOPA Decarboxylase

Anti-DOPA Decarboxylase

Specific for the ~55k DDC protein in Western blots. Prepared from sheep serum by affinity purification using an AminoLink Plus column matrix to which purified, recombinant bovine DDC was coupled.

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SPECIFICATIONS

Size

100 ul

Applications

WB

Hosts

Sheep

Reactivities

Hum, Rat, Bov, Can, Prc, Rabbit, Sheep

Format

Affinity purified, polyclonal antibody

Presku

OAPC00101

Target

DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

Weight

~55kDa

Gene Id

280762

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